Department of Biology
Minority Health International Research Training
 CBU's MHIRT Web Page     CBU Biology    CBU Biology Events
São Paulo, Brazil
  • São Paulo Projects (current):
  • More MHIRT Projects, how to apply, etc.

  • Drs. Toledo, Marques, and Carobrez (at CBU, Nob. 2007)
    | Map of Brazil |   | Another Map |
    | Dr. Toledo's Photos of Brazil |
    | São Paulo Brazil |    | More about São Paulo |
    | Universities & Research Labs |
    Dr. Luiz Britto's Lab, Univ. São Paulo
    2002 Photos by Dr. Fitzgerald  [Click to see a larger image.]

    Dr. Luiz Britto and Eckardt Campos (MIRT 2002 student)

    Eckardt processing tissue

    Claudio preparing for seminar

    Lab members in Dr. Britto's lab

    Other members in Dr. Britto's lab

    Dr. Britto and lab at dinner
    Dr. Claudio Toledo's Lab, City University of São Paulo
    2002 Photos by Dr. Fitzgerald  [Click to see a larger image.]

    Monique on the computer

    Dr. Caudio Toledo and Fatima in Dr. Toledo's office

    Lachre taking notes

    Monique and Dr. Toledo processing tissue

    View of UNICID from the metro

    Walking to the lab

    Dr. Fitzgerald and Monique cutting tissue

    Lachre and Monique cutting tissue

    Marcia, Dr. Toledo's Lab Technician

    Monique mounting tissue

    Lachre processing tissue

    Summary of Dr. Toledo's Presentations at CBU on 14 and 16 Nov. 2000
    Research in the Neurobiology of Visual Systems
    Cláudio A. B. Toledo
    City University of São Paulo
    São Paulo, SP  -  Brazil
  • Educational Background:
  • B.S. Biology - 1984.  Marine Biology (invertebrates)
    M.S.  Physiology & Biophysics - 1989.  Animal Behavior  (ethology)
    Ph.D. Physiology & Biophysics - 1994.  Neurophysiology
  • Research Goals:  To better understand the neural basis of the sensory-motor brainstem integration with major emphasis of the sub-cortical visual pathways.

  •  
  • What tools are used?
  • Neuroanatomical techniques:

  • - histochemistry
    - immunohistochemistry
    - selective neuronal lesions
    - neural tract-tracing
    • Understanding the neural micro-circuitry: a technical approach.  Beyond anatomical dissection.
    • Identifying the neural structures: 

    •   - by classical histological techniques:  stains (Nissl, Giemsa, Neutral red, Evans, etc.)
        - by recent histological techniques:  histochemistry; immunohistochemistry
    • Identifying the neural structures.  What neural structures?   Cells - Nuclei - Pathways
    • Neurochemical Identification (NI) of Cells and Nuclei

    •      - neurotransmitters
           - neuromodulators
           - receptors
          - other proteins:  structural; metabolic
    • Hodological Identification (HI) of Pathways 

    •       - lesions
            - neurotracers
            - anterograde
            - retrograde
            (microinjections done by pressure or iontophoresis)
    • Functional aspects of the pathways:  Combine NI & HI with Behavioral Procedures (BP)
    • Equivalency and/or homology of neural structures:  Combine NI, HI, & BP with an embryological criteria.
    • Model organism:  pigeon.
  • A view of Brazil in photographs provided by Dr. Toledo.

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