COURSE: Neuroscience 451Lecture Syllabus

INSTRUCTOR: Dr. Malinda E.C. Fitzgerald

Office Hours: Science 203E

Monday 9:00-11:00 and 1:00-4:00

Tuesday 9:00-11:00*

* times may change during semester

Thursday Off Campus Research Day, available at UT 448-5724

Appointments can be arranged at other times, just see me in class or call and arrange.

Office phone 321-3262; Digital pager 762-3830

TEXT: Principles of Neural Science, Kandel, Schwartz and Jessell

Neuroanatomy: An Atlas of Structures , Sections and Systems, Haines

Suggested Text: Neuroscience: An Outline Approach, Castro et al.,

Goals: To obtain an understanding of the structure and function of the nervous system as we know it today.

OVERVIEW: The field of Neuroscience is a large and rapidly expanding field. Many disciplines are involved in the study of the function of the nervous system. This course is an overview of the neuroscience field. An emphasis will be placed in this course on the neuroanatomy of the mammalian brain. (Its histology and connections). In addition neurophysiology and neuropharmacology of both vertebrate and invertebrate systems will be discussed. Truly the brain is a frontier. We know a great deal about how the brain functions yet we still have so much to learn. Discussions within this class will also include some clinical implications of neurodegenerative diseases. In the laboratory we will utilize the resources available to us within the Center For Neuroscience at the University of TN, University of Memphis, and SCO as well as CBU.

ATTENDANCE: Students are required to attend all lectures, and labs. Some of the labs will require transportation to another location. Students must be present for all scheduled exams. All exams will be comprehensive to some degree, because you will have to integrate material from the previous exam. Make up exams will be given if a valid reason is given. These exams will not be the same as previously administered to the class. Exams will not be returned, however they will be available for review. Discussion within the class is a necessary component of your grade. I expect you to be able to interact and discuss issues concerning social, economic and biological impact of neuroscience on both you as an individual and the society at large.

GRADING PROTOCOL:

1. Three exams worth 100 points each. These exams will be comprehensive and will included multiple choice, short answer and essay format. (Part of these will not be taken in class)

2. Journal articles. Part of understanding science is reading the literature. You will be assigned journal articles through the semester or material assigned in class (25 points each). There will be 6-8 of these.

3. Research Project. You will be given a choice of research projects or you may suggest your own. This project will be completed by Nov. 17th and a written report turned in by this time. The projects will be presented to the class in the lab period. (200 points total)

3. One comprehensive final exam will be given. This will be scheduled during exam week. This will be worth 200 points. If you have an overall grade of 95 you will be exempt from the final exam.

5. The grading scale will be 90-100=A, 80-89=B, 70-79=C, 60-69=D, <59=F.

This is a suggested Lecture Schedule. I reserve the right to modify the topic order and modify the test dates as necessary in the semester.

Week

Dates

Chapter in Kandell

Topic

1

8/25-8/30

Chapters 1,4, 5

Introduction

2

9/1-9/3

Chapter 17, 6

Neuronal Organization

3/4

9/8-9/13

 

Chapter 7-9

Action potential and membrane properties

4/5

9/15-19/20

Chapter 10-16

Synapse, neurotransmitters

EXAM

9/22

Material Covered

Exam I

5/6

9/24-9/29

Chapter 52-56

Development of Nervous System

6/7

10/1-10/4

Chapter 18-20

(Cont) Development

Perception and Movement

7/8

10/6-10/11

Chapters 21-24

Body Senses

8

10/13-10/15

Chapter 25-29

Visual System

9

FALL BREAK

FALL BREAK

FALL BREAK

10

10/25-10/29

Chapters 30, 40

Finish Visual and other senses

EXAM

11/1

Material Covered

Exam II

11

11/3-11/5

Chapters 33-38 selected parts of

40-45

Movement and Injury

12

11/8-11/12

Chapters 44-51

Chemical Basis of Behavior

EXAM

11/12

Take Home

Exam III

13

11/15-11/19

Chapter 57 and readings

Sexual Difference in Nervous System

14

11/22-11/24

Chapters 59-63

Language/Memory

14

Holiday

Thanksgiving

Holiday

15

11/29-12/3

Readings and previous chapters

Memory and Diseases

16

12/6-12/10

Special Topics in Neurscience

All subjects!

17

FINAL EXAM

FINAL EXAM

FINAL EXAM