Termination of drug action and the excretory system

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Termination of drug action and the excretory system

Routes through which drugs can leave the body include:

Most drugs leave the body via urine

Note the regular arrangement of tissue in the liver in this cross-section:

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These metabolite molecules diffuse into the bloodstream and continue to the kidneys, whose functional units are called nephrons:

Suppose that we’re dealing with a therapeutic drug which must be taken as a maintenance drug on an ongoing basis.

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Termination of drug action and the excretory system