Dr. Sandra Thompson-Jaeger
Associate Professor of Biology

CW114

901.321.3453

sthompso@cbu.edu

Homepage: http://www.cbu.edu/~sthompso

 
Genetics (BIOL311)

 

Course description: A study of the structure and function of nucleic acids in viruses, prokaryotes and eukaryotes. Basic concepts, principles and applications of classical, molecular and population genetics. Prerequisites: Grade of C or better in BIOL 112 and CHEM 212. Corequisite: BIOL 311L. Offered in the Fall semester.  One semester, three credits.

 

Required textbook:

Concepts of Genetics, 9th edition

Klug, Cummings, Spencer, Palladino

 

Objectives: to learn and understand classical, molecular and population genetics; to gain information literacy; to become aware of recent topics in Genetics.

 

Grading: Each of the four exams given during lecture periods will be 100 points.  Exams may include problems; multiple choice, fill in the blank, and short answer questions. The fifth exam, given during Finals week, will be cumulative and worth 150 points.

There will be one 30-point information literacy assignment.

There will be four quizzes and three homework (problem) assignments.

Total points possible are about 690.

 

Make-up exam/quiz policy: Make-up exams will be given only for very compelling, documented reasons, which include severe illness and a death in the immediate family. Make-up exams will likely have a different format from the regularly scheduled exams. If you know you are going to miss an exam because of a death in the family, funeral, surgery, etc. you must come to me BEFOREHAND so we can arrange for the make-up exam. If you are too ill to come and take an exam, call me or leave a message with Ms. Leah Allen (administrative assistant in the School of Sciences). If you are ill, I MUST see a doctor's note when you return to class.
There will be no make-up quizzes, but in the last week I will give a "general amnesty quiz" which you may take, if you so choose; the grade on this quiz can replace your lowest grade on any one of the other four quizzes.

Grading scale: 100-90% = A; 80-89% = B; 70-79% = C; 60-69% = D; below 60% = F

 

How to do well in this course: Make every attempt to be present for every lecture. (If you are absent, it is your responsibility to contact a classmate to find out what you missed, which includes any announcements about quizzes, homework, etc.)

Read the Chapter Summary for each assigned chapter before and after you read the chapter. Ideally you will read chapters before they are covered in class. Make careful notes and be prepared to ask questions on those topics that you did not understand. This will help us get the most out of lecture time. You will be responsible for any assigned reading, not just topics covered in class.

Problem solving is a BIG part of genetics. You should study genetics the same way that you study for a math course. Indeed, a fellow Prof once said to me "Genetics is really math masquerading as biology". If you do not do any practice problems before exams, you may only be able to get through two-thirds of the exam in the allotted time. You must consider that is not because the test is too long, but because you did not adequately prepare.

Study and review the material in small groups.

Please ask questions about concepts you do not understand. If you do not want to ask during lecture period, e-mail me or come by my office. If no one asks questions during lecture periods, I will have to assume you all understand the material.

 

 

Topic Schedule:

Week

Topics

Text/assignments

1: August 24-28

Newest trends

Mitosis, Meiosis
Mendel

Ch 1 (Read on your own)

Ch 2
Ch 3

2: August 31-
September 4

Mendel, cont.

Probabilities, pedigrees
Extending Mendelian Genetics

Ch 3

Problem set (10)
Ch 4

3: September 9-11

Extending Mendelian genetics, cont.

Chromosome mapping

Ch 4

Problem set (10)

Ch 5

4: September 14-18

Genetic analysis in bacteria

EXAM I (FRIDAY)

Ch 6

5: September 21-25

Sex chromosomes

Chromosome mutations
Extranuclear inheritance

Ch 7

Ch 8

Ch 9

6: September 28-
October 2

DNA structure/analysis

DNA replication

Ch 10

Ch 11
QUIZ

7: October 5-9

Telomeres, recombination

Chromosome organization

Recombinant technology

Ch 11

Ch 12

Ch 13

8: October 12-16

Recomb tech, cont.

EXAM II (WED)

Genetic code, transcription

Ch 13

 

Ch 14

9: October 19-23

REST! Enjoy your fall break

 

10: October 27-31

Translation, proteins

Mutation, repair

Prok gene regulation

Ch 15

Ch 16

Ch 17

11: November 2-6

Prok gene regulation

Euk gene regulation

Ch 17

Ch 18

QUIZ

12: November 9-13

Developmental genetics

Cancer/cell cycle

EXAM III (Friday)

Ch 19

Ch 20

 

13: November 16-20

Human Genome project

Transposons, viruses

Dissecting gene function

Ch 21

Ch 22

Ch 23

14: November 23-25

Edible vaccines, GM crops

Quantitative genetics

Ch 24

Ch 25

QUIZ

15: November 30-
December 4

Population genetics

Ch 27

Problem set (10)

16: December 7-11

Genetics and behavior

Genetics in the news

EXAM IV (Friday)

Ch 26

 

December 14-18: EXAM V (during Finals week).

 

The topic schedule shown above is SUBJECT TO CHANGE.

 

Anyone found cheating may be given an F for the course.

According to university policy, eight hours of absence from lecture or lab will result in a failing grade for the course.

During lecture, please ensure that all beepers, pagers, cell phones, and laptops are turned off or silenced (unless you are told otherwise).